Radiological and functional outcome of allografts in orthopaedics
|IJOCP | Volume – 2015| Issue – 2015| Article ID – 2015:86
Conference: Indian Orthopaedic Association Annual Conference IOACON-2013, India [Click for Full details]
Authors: Natesan R, Devendra A
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Introduction: Harvesting of autografts results in donor site morbidity, another surgical procedure. The bridging of large bone defects for tumours or trauma reconstruction poses a major challenge for orthopaedic surgeons. Allogarfts provide a suitable alternative in enormous cost savings, operational time. Allografts gives the benefit of being available in large quantities in desired shapes and size. Aim of the study: The main aim of the study is to analyse the utility, safety, complication rates, radiological and functional outcome of allografts used in the field of orthopaedics.
Methods: The study is a retrospective cross sectional study on allografts used in 81 patients (83 anatomical sites) of Ganga Hospital for a period of two and half years from Jan 2010 to june 2012, with a minimum follow up period of one year. Patients were grouped in to spine surgery, arthroplasty, trauma surgery and tumour surgery. Outcome of surgery is assessed on the basis of functional and radiological assessment.
Results: Time for incorporation were calculated for each group. For morcellised graft it was found to be 7.73 months and for structural graft, it was 14.11 months. We found that 93% (77 anatomical sites) had good incorporation of graft. There was 100% rate of incorporation of graft without any major complications in the paediatric population, spine fusion surgeries, arthroplasty and bone tumour surgeries. The infection rate was 7.4% (6 patients) and the non-union rate was 7.4%. Among infection group we found that 83% of the cases had open injury and 30% of patients were diabetic, suggesting that the source of infection was not the irradiated grafts. We found that bone gap up to 50 mm can be reconstructed with mixed morcellised allograft and autograft, and bone loss up to 120 mm can be reconstructed with structural allograft.
Conclusion: Gamma irradiated bone allografts can be reliably used in orthopaedic procedures. Surgical Procedure is simple, safe, reduces blood loss, easily reproducible procedure with reduced morbidity and durable biological reconstruction compared to autografts.
|How to Cite this Abstract|
|Natesan R, Devendra A . Radiological and functional outcome of allografts in orthopaedics. International Journal of Conference Proceedings 2015;(2015):86|